In the urothelium, umbrella cells are characterised by apical expression of transmembrane uroplakins that add to transcellular barrier function65,71, though the paracellular barrier is managed by intercellular limited junctions with claudin proteins defining the paracellular permeability117,123. Hi?n nay có r?t nhi?u trò ch?i cá c??c m?i l? n